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Results show that the hydraulic resistance is significantly reduced in the proposed four ports actuators; and the proposed cylinders run faster than the conventional cylinders and a considerable amount of energyis saved as well.

Key words: Computational Hydraulic, Energy Efficient Actuators, Energy Saving in Hydraulic, Hydraulic Control Reference [1] P.

The proposed four ports cylinder was simulated and parameters such as ports sizes, loads and pressures are varied during the simulation.

The hydraulic resisting forces, piston speed and mass flow rates are computed. Chenoweth, Aircraft flight control actuation system design vol.

Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot.

Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press.

Eberhart "Fuzzy Adaptive Particle Swarm Optimization" Evolutionary computation, 2001 proceeding of the 2001 congres on vol.1 page no.

Gaing, "Particle Swarm Optimization to solving the economic dispatch considering generator constraints," IEEE Trans.

Palmberg, "Hydraulic transformers-comparison of different designs," 2004. The organism requires minimal set of functional genes for its survival. Bateman A, Birney E, Cerruti L (2002).‖The Pfam Protein Families Database‖. Two kinds of improved evolution rules are proposed to replace the rule in regular cellular genetic algorithm, in which null cells are considered to the foods of individuals in population and the maximum of living individuals in cellular space is limited by their food.

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